PD-L1 antibody (AA 39-191)
-
- Target See all PD-L1 Antibodies
- PD-L1 (CD274 (PD-L1))
-
Binding Specificity
- AA 39-191
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This PD-L1 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant fragment of human CD274 protein (around aa 39-191) (exact sequence is proprietary)
- Clone
- PDL1-2743
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product PD-L1 Primary Antibody
-
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6D9A2 unconjugated
anti-CD274 (PD-L1) (AA 39-191) antibodyPD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated
anti-CD274 (PD-L1) (AA 48-290) antibodyPD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (Extracellular Domain) antibodyPD-L1 Reactivity: Human IHC Host: Rabbit Monoclonal unconjugated
anti-CD274 (PD-L1) (AA 34-241) antibodyPD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 24-153) antibodyPD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC Host: Mouse Monoclonal 7D2A10 unconjugated
anti-CD274 (PD-L1) (C-Term) antibodyKO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-CD274 (PD-L1) (AA 19-238) antibodyPD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
-
- Application Notes
-
Positive Control: Heart, Placenta, Spleen or Tonsil (IHC). Jurkat cells (IF/FACS).
Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/mL),Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
-
- Target
- PD-L1 (CD274 (PD-L1))
- Alternative Name
- CD274 (PD-L1 Products)
- Synonyms
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- Background
- PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
- Molecular Weight
- 37-50kDa
- Gene ID
- 29126
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
-
