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Recombinant CD31 antibody

PECAM1 Reactivity: Human FACS, WB, IHC, StM Host: Rabbit Monoclonal C31-1395R unconjugated Recombinant Antibody
Catalog No. ABIN6940290
  • Target See all CD31 (PECAM1) Antibodies
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 268
    • 129
    • 71
    • 59
    • 41
    • 28
    • 22
    • 18
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 151
    • 147
    • 36
    • 7
    • 3
    • 2
    Rabbit
    Clonality
    • 212
    • 133
    • 1
    Monoclonal
    Conjugate
    • 149
    • 32
    • 30
    • 23
    • 11
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD31 antibody is un-conjugated
    Application
    • 216
    • 182
    • 95
    • 84
    • 60
    • 37
    • 32
    • 30
    • 26
    • 26
    • 19
    • 15
    • 13
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    Specificity
    CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human CD31 protein
    Clone
    C31-1395R
    Isotype
    IgG
  • Application Notes

    Positive Control: THP-1, Jurkat cells. Tonsil or Angiosarcoma.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Alternative Name
    PECAM1 (PECAM1 Products)
    Synonyms
    CD31 antibody, CD31/EndoCAM antibody, GPIIA' antibody, PECA1 antibody, PECAM-1 antibody, endoCAM antibody, C85791 antibody, Cd31 antibody, Pecam antibody, platelet/endothelial cell adhesion molecule 1 antibody, platelet and endothelial cell adhesion molecule 1 antibody, pecam1 antibody, PECAM1 antibody, Pecam1 antibody
    Molecular Weight
    ~100kDa (endothelium) and ~130kDa (platelets)
    Gene ID
    5175
    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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