Prolactin Receptor antibody

Catalog No. ABIN6940406

Product Details anti-Prolactin Receptor Antibody

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificity: It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Purification: Purified by Protein A/G

Immunogen: Semi-Purified human prolactin receptor (B6.2), Recombinant human prolactin receptor (PRLR742)

Clone: B6-2-PRLR742

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Testicular Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR (PRLR Products)

Synonyms: hPRLrI antibody, PRL-R antibody, prlr antibody, PRLRb antibody, PRLR antibody, tprlr antibody, DKFZp469D061 antibody, RATPRLR antibody, AI987712 antibody, Pr-1 antibody, Pr-3 antibody, Prlr-rs1 antibody, wu:fj65c07 antibody, prolactin receptor antibody, prolactin receptor L homeolog antibody, prolactin receptor S homeolog antibody, prolactin receptor a antibody, PRLR antibody, prlr.L antibody, prlr.S antibody, PR antibody, prlr antibody, Prlr antibody, prlra antibody

Molecular Weight: 70kDa

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus