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S100B antibody

S100B Reactivity: Human, Rat, Mouse, Cow WB, IHC, IF, FACS, StM Host: Mouse Monoclonal S100B-1012 unconjugated
Catalog No. ABIN6940557
  • Target See all S100B Antibodies
    S100B (S100 Calcium Binding Protein B (S100B))
    Reactivity
    • 157
    • 93
    • 62
    • 44
    • 18
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow
    Host
    • 127
    • 66
    • 7
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 114
    • 91
    Monoclonal
    Conjugate
    • 84
    • 31
    • 21
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This S100B antibody is un-conjugated
    Application
    • 140
    • 80
    • 64
    • 59
    • 48
    • 25
    • 25
    • 19
    • 18
    • 15
    • 13
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Specificity
    The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human S100B protein
    Clone
    S100B-1012
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product S100B Primary Antibody
  • Application Notes

    Positive Control: Brain, Melanoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Western Blot (0.5-1 μg/mL),Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    S100B (S100 Calcium Binding Protein B (S100B))
    Alternative Name
    S100B (S100B Products)
    Synonyms
    NEF antibody, S100 antibody, S100-B antibody, S100beta antibody, S100P antibody, AI850290 antibody, Bpb antibody, si:dkey-110p14.2 antibody, wu:fq18b10 antibody, zgc:92776 antibody, S100 calcium binding protein B antibody, S100 protein, beta polypeptide, neural antibody, S100 calcium binding protein, beta (neural) antibody, S100B antibody, S100b antibody, s100b antibody
    Molecular Weight
    10-12kDa
    Gene ID
    6285
    UniProt
    P04271
    Pathways
    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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