Defensin beta 3 antibody (AA 23-67) (Alexa Fluor 350)

Catalog No. ABIN6942252

Product Details anti-Defensin beta 3 Antibody (Alexa Fluor 350)

Target: Defensin beta 3 (DEFB3)

Binding Specificity: AA 23-67

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Defensin beta 3 antibody is conjugated to Alexa Fluor 350

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta Defensin 3

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Defensin beta 3

Target: Defensin beta 3 (DEFB3)

Alternative Name: beta Defensin 3 (DEFB3 Products)

Synonyms: BD-3 antibody, DEFB-3 antibody, DEFB103 antibody, DEFB3 antibody, HBD3 antibody, HBP-3 antibody, HBP3 antibody, hBD-3 antibody, BNBD-3 antibody, BNBD-6 antibody, BNDB-3 antibody, BNDB-6 antibody, BNDB3 antibody, DEFB103A antibody, DEFB2 antibody, DEFB6 antibody, bnbd3 antibody, defb405 antibody, defensin beta 103A antibody, defensin beta 3 antibody, beta-defensin 3 antibody, DEFB103A antibody, Defb3 antibody, DEFB3 antibody

Background:

Synonyms: BD 3, BD-3, BD3, beta 103, Beta defensin 103A, Beta defensin 103A precursor, Beta defensin 3, Beta-defensin 103, Beta-defensin 3, D103A_HUMAN, DEF B3, DEFB 103, DEFB 103A, DEFB 3, DEFB-3, DEFB103, DEFB103A, DEFB103B, DEFB3, Defensin, Defensin beta 103A, Defensin beta 3, Defensin like protein, Defensin-like protein, HBD 3, hBD-3, HBD3, HBP 3, HBP3, mBD3.

Background: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.

Gene ID: 414325

UniProt: P81534

Pathways: Production of Molecular Mediator of Immune Response