EIF2B1 antibody (AA 51-150)

Catalog No. ABIN6943232

Product Details anti-EIF2B1 Antibody

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Binding Specificity: AA 51-150

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human eIF2B1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EIF2B1

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Alternative Name: eIF2B1 (EIF2B1 Products)

Background:

Synonyms: 26 kDa, D5Ertd406e, EI2BA, eIF 2a, EIF 2B, eIF 2B GDP GTP exchange factor subunit alpha, EIF 2Balpha, EIF2B alpha, EIF2B, EIF2B1, EIF2BA, eukaryotic translation initiation factor 2B subunit 1 alpha, Eukaryotic translation initiation factor 2B, alpha, eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD), Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26 kDa, MGC117409, MGC125868, EI2BA_HUMAN, MGC125869, MGC6458, Translation initiation factor eIF2B subunit alpha, zgc:86660.

Background: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]

Gene ID: 1967

UniProt: Q14232

Pathways: Methionine Biosynthetic Process