NFKB2 antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2)

Details for Product anti-NFKB2 Antibody No. ABIN6944281
Antigen
  • NF-kappaB2
  • lyt
  • p49
  • p49/p100
  • p50B
  • p52
  • nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
  • Nfkb2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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142
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11
6
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2
1
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1
Host
Rabbit
291
6
Clonality (Clone)
Monoclonal ()
Conjugate
This NFKB2 antibody is un-conjugated
14
8
8
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7
7
7
4
3
2
2
2
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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127
90
61
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37
12
12
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Options
Immunogen C terminal human NFkB p100
Clone 5G1
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others NFKB2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name NFkB p100 (NFKB2 Antibody Abstract)
Background

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.


Synonyms: Nuclear factor NF-kappa-B p100 subunit, DNA-binding factor KBF2, H2TF1, Lymphocyte translocation chromosome 10 protein, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Oncogene Lyt-10, Lyt10, NFKB2, LYT10
Gene ID 4791
UniProt Q00653
Pathways Toll-Like Receptors Cascades
Application Notes WB(1:500-2000), IHC-P(1:50-200), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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