OGG1 antibody (8-Oxoguanine DNA Glycosylase)

Details for Product anti-OGG1 Antibody No. ABIN6944353
Antigen
  • OGG1
  • zgc:158858
  • 8-oxoguanine-DNA glycosylase 1
  • ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1
  • ATOGG1
  • F8K7.14
  • F8K7_14
  • 19.m02329
  • DDBDRAFT_0184479
  • DDBDRAFT_0233024
  • DDB_0184479
  • DDB_0233024
  • ogg1
  • Tb04.1H19.930
  • HMMH
  • HOGG1
  • MUTM
  • OGH1
  • Mmh
  • 8-oxoguanine DNA glycosylase
  • 8-oxoguanine DNA glycosylase L homeolog
  • 8-oxoguanine-DNA glycosylase 1
  • 8-OXOGUANINE DNA GLYCOSYLASE
  • putative 8-oxoguanine DNA glycosylase
  • 8-oxoguanine DNA-glycosylase
  • N-glycosylase/DNA lyase OGG1
  • 8-oxoguanine DNA-glycosylase 1
  • OGG1
  • ogg1.L
  • ogg1
  • ECU08_0770
  • CA_C2707
  • BBOV_I004290
  • Smp_074010.1
  • LOC9329243
  • Tb927.4.2480
  • Ogg1
Reactivity
Human
92
52
52
3
2
2
1
1
Host
Rabbit
89
8
6
Clonality (Clone)
Monoclonal ()
Conjugate
This OGG1 antibody is un-conjugated
7
5
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
67
31
23
13
6
5
5
2
1
1
1
Options
Immunogen N terminal human OGG1
Clone 9F3
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others OGG1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name OGG1 (OGG1 Antibody Abstract)
Background

DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.

Subcellular location: Nucleus, Mitochondrion


Synonyms: N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase, AP lyase, OGG1, MMH, MUTM, OGH1
Gene ID 4968
UniProt O15527
Pathways DNA Damage Repair
Application Notes IHC-P(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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