MAPK14 antibody (Mitogen-Activated Protein Kinase 14)

Details for Product anti-MAPK14 Antibody No. ABIN6944382
Target
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38
  • p38ALPHA
  • CRK1
  • Csbp1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • p38alpha
  • p38b
  • zp38b
  • MAPK14
  • 186F5S
  • BG:DS00797.3
  • CG7393
  • D-p38
  • D-p38 MAPK
  • D-p38b
  • Dm p38b
  • Dmel\\CG7393
  • Dmp38b
  • Dp38
  • Dp38b
  • ESTS:186F5S
  • Mpk34C
  • anon-sts23
  • dp38b
  • p38 MAPK
  • p38 beta
  • p38B
  • p38Kb
  • p38beta
  • Crk1
  • p38-alpha
  • p38MAPK
  • p38a
  • csbp
  • mapk14a
  • mxi2
  • sapk2
  • sapk2a
  • AP22.98
  • AP22_98
  • ATMPK14
  • mitogen-activated protein kinase 14
  • SAPK2a
  • MAP kinase 14A
  • MAP kinase p38a
  • MAPK 14A
  • fk28c03
  • hm:zeh1243
  • wu:fk28c03
  • zp38a
  • P38C-CRK
  • mitogen-activated protein kinase 14
  • mitogen activated protein kinase 14
  • mitogen-activated protein kinase 14b
  • p38b MAP kinase
  • mitogen-activated protein kinase 14 S homeolog
  • mitogen-activated protein kinase 14a
  • CRK proto-oncogene, adaptor protein
  • MAPK14
  • Mapk14
  • mapk14b
  • p38b
  • mapk14.S
  • MPK14
  • mapk14a
  • CRK
Reactivity
Human, Mouse, Rat
353
243
221
55
41
40
38
35
34
34
28
28
17
15
6
3
3
2
1
1
1
1
Host
Rabbit
284
70
2
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This MAPK14 antibody is un-conjugated
22
14
11
9
9
8
8
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Western Blotting (WB)
287
160
144
93
69
43
37
27
26
24
14
14
6
6
5
2
2
1
1
1
1
1
1
Options
Immunogen Human p38 MAPK aa 800 to the C-terminus
Clone 10B7
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name p38 MAPK (MAPK14 Antibody Abstract)
Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]


Synonyms: Mitogen-activated protein kinase 14, Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, Stress-activated protein kinase 2a, MAP kinase 14, MAPK 14, CSAID-binding protein, CSBP, MAP kinase p38 alpha, SAPK2a, MAPK14
Gene ID 1432
UniProt Q16539
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling
Application Notes WB(1:300-1000), IF(ICC)(1:50-200), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months