PDCD4 antibody (Programmed Cell Death 4 (Neoplastic Transformation Inhibitor))

Details for Product anti-PDCD4 Antibody No. ABIN6944460
Antigen
  • H731
  • D19Ucla1
  • Ma3
  • Tis
  • Dug
  • cb45
  • pdcd4
  • sb:cb45
  • wu:fc84b08
  • h731
  • MGC69337
  • PDCD4
  • programmed cell death 4
  • programmed cell death 4b
  • programmed cell death 4 L homeolog
  • programmed cell death 4 (neoplastic transformation inhibitor)
  • PDCD4
  • Pdcd4
  • pdcd4b
  • pdcd4.L
  • pdcd4
Reactivity
Human, Mouse (Murine)
232
146
129
13
10
9
7
7
7
6
5
5
5
3
3
1
1
1
1
Host
Rabbit
202
23
8
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PDCD4 antibody is un-conjugated
10
6
6
6
6
6
6
4
4
3
3
3
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
174
105
90
38
20
15
11
8
8
7
3
2
2
Options
Immunogen Full length protein
Clone 3G1
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PDCD4 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PDCD4 (PDCD4 Antibody Abstract)
Background

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).


Synonyms: Programmed cell death protein 4, Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, Protein 197/15a, PDCD4, H731
Gene ID 27250
UniProt Q53EL6
Application Notes FCM(1:50-100), IHC-P(1:50-200), IF(IHC-P)(1:50-200), IF(ICC)(1:20-50)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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