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PKC epsilon antibody

PRKCE Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p), FACS, IHC (p) Host: Rabbit Monoclonal 6B4 unconjugated
Catalog No. ABIN6944555
  • Target See all PKC epsilon (PRKCE) Antibodies
    PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
    Reactivity
    • 90
    • 66
    • 53
    • 6
    • 3
    • 2
    Human, Mouse, Rat
    Host
    • 119
    • 6
    • 1
    Rabbit
    Clonality
    • 112
    • 14
    Monoclonal
    Conjugate
    • 51
    • 13
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKC epsilon antibody is un-conjugated
    Application
    • 100
    • 52
    • 28
    • 27
    • 27
    • 15
    • 9
    • 8
    • 8
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    C terminal human PKC epsilon
    Clone
    6B4
    Isotype
    IgG
    Top Product
    Discover our top product PRKCE Primary Antibody
  • Application Notes
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
    Alternative Name
    PKC epsilon (PRKCE Products)
    Synonyms
    PKCE antibody, nPKC-epsilon antibody, 5830406C15Rik antibody, PKC[e] antibody, PKCepsilon antibody, Pkce antibody, R75156 antibody, fj59b07 antibody, prkce antibody, wu:fj59b07 antibody, pkce antibody, pkc-epsilon antibody, PRKCH antibody, protein kinase C epsilon antibody, protein kinase C, epsilon antibody, protein kinase C, epsilon a antibody, PRKCE antibody, Prkce antibody, prkcea antibody, prkce antibody
    Background

    Synonyms: Protein kinase C epsilon type, nPKC-epsilon, PRKCE, PKCE

    Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

    Gene ID
    5581
    UniProt
    Q02156
    Pathways
    TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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