PRNP antibody (Prion Protein)

Details for Product anti-PRNP Antibody No. ABIN6944654
Antigen
  • ASCR
  • AltPrP
  • CD230
  • CJD
  • GSS
  • KURU
  • PRIP
  • PrP
  • PrP27-30
  • PrP33-35C
  • PrPc
  • p27-30
  • Prn
  • Prn-p
  • prp
  • cjd
  • prion
  • prp(c)
  • MGC84114
  • PRP
  • PRPC
  • Prp
  • SIP
  • PRNP
  • AA960666
  • AI325101
  • PrP
  • PrPC
  • PrPSc
  • Prn-i
  • Sinc
  • prP27-30
  • prP33-35C
  • PrP-1
  • PrP1
  • prnprs1
  • stPrP-1
  • zgc:123004
  • prion protein
  • prion protein S homeolog
  • prion protein b
  • PRNP
  • Prnp
  • prnp.S
  • prnpb
Reactivity
Human, Mouse (Murine), Rat (Rattus)
136
86
84
27
23
4
2
2
1
1
1
1
Host
Rabbit
127
38
13
3
Clonality (Clone)
Monoclonal ()
Conjugate
This PRNP antibody is un-conjugated
10
6
6
5
5
5
5
5
5
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Western Blotting (WB)
117
62
51
29
26
13
7
6
5
5
5
4
2
1
Options
Immunogen C terminal human Prion protein
Clone 33A5
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PRNP products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Prion Protein (PrP) (PRNP Antibody Abstract)
Background

The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).


Synonyms: Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP
Gene ID 5621
UniProt P04156
Pathways Transition Metal Ion Homeostasis, Activated T Cell Proliferation
Application Notes WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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