Transportin 3 antibody

Catalog No. ABIN6945191

Product Details anti-Transportin 3 Antibody

Target: Transportin 3 (TNPO3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Transportin 3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human TNPO3 aa 800-950.

Clone: 11F2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Transportin 3

Target: Transportin 3 (TNPO3)

Alternative Name: TNPO3 (TNPO3 Products)

Synonyms: zgc:55409 antibody, tnpo3 antibody, MGC82948 antibody, TNPO3 antibody, DKFZp459J2330 antibody, IPO12 antibody, MTR10A antibody, TRN-SR antibody, TRN-SR2 antibody, TRNSR antibody, 5730544L10Rik antibody, C430013M08Rik antibody, C81142 antibody, D6Ertd313e antibody, Trn-SR antibody, mKIAA4133 antibody, transportin 3 antibody, transportin 3 S homeolog antibody, transportin-SR antibody, tnpo3 antibody, TNPO3 antibody, tnpo3.S antibody, Bm1_43850 antibody, LOAG_04608 antibody, Tnpo3 antibody

Background:

Synonyms: Transportin-3, Importin-12, Transportin-SR, Imp12, TRN-SR, TNPO3, IPO12

Background: TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2 by recognizing phosphorylated RS domains. TNPO3 has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene

Gene ID: 23534

UniProt: Q9Y5L0

Pathways: Protein targeting to Nucleus