ZGPAT antibody (AA 431-531) (Biotin)

Catalog No. ABIN6945423

Product Details anti-ZGPAT Antibody (Biotin)

Target: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Binding Specificity: AA 431-531

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZGPAT antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZGPAT

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ZGPAT

Target: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Alternative Name: ZGPAT (ZGPAT Products)

Synonyms: zc3h9 antibody, gpatc6 antibody, gpatch6 antibody, zc3hdc9 antibody, GPATC6 antibody, GPATCH6 antibody, KIAA1847 antibody, ZC3H9 antibody, ZC3HDC9 antibody, ZIP antibody, 1500006I01Rik antibody, BC021513 antibody, RGD1310801 antibody, zgc:63730 antibody, zinc finger CCCH-type and G-patch domain containing antibody, zinc finger, CCCH-type with G-patch domain L homeolog antibody, zinc finger, CCCH-type with G-patch domain antibody, zinc finger, CCCH-type with G patch domain antibody, ZGPAT antibody, zgpat.L antibody, zgpat antibody, Zgpat antibody

Background:

Synonyms: dJ583P15.3, FLJ14972, G patch domain-containing protein 6, GPATC6, GPATCH6, KIAA1847, MGC44880, RP4 583P15.3, ZC3H9, ZC3HDC9, ZGPAT, ZGPAT_HUMAN, Zinc finger and G patch domain-containing protein, Zinc finger CCCH domain-containing protein 9, Zinc finger CCCH type with G patch domain1, Zinc finger CCCH-type with G patch domain-containing protein, ZIP.

Background: ZGPAT is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.

Gene ID: 84619

UniProt: Q8N5A5

Pathways: EGFR Signaling Pathway