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KREMEN2 antibody (AA 351-450) (HRP)

KREMEN2 Reactivity: Mouse, Rat WB, ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN6943889
  • Target See all KREMEN2 Antibodies
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 20
    • 16
    • 15
    Mouse, Rat
    Host
    • 31
    • 3
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KREMEN2 antibody is conjugated to HRP
    Application
    • 34
    • 17
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KREMEN2
    Isotype
    IgG
    Top Product
    Discover our top product KREMEN2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Alternative Name
    KREMEN2 (KREMEN2 Products)
    Synonyms
    krm2 antibody, KREMEN2 antibody, MGC147633 antibody, KRM2 antibody, 2900054E04Rik antibody, Krm2 antibody, kringle containing transmembrane protein 2 S homeolog antibody, kringle containing transmembrane protein 2 antibody, kremen2.S antibody, KREMEN2 antibody, kremen2 antibody, Kremen2 antibody
    Background

    Synonyms: Dickkopf receptor 2, KREM2_HUMAN, KREMEN 2, Kremen protein 2, Kremen protein 2 precursor, Kremen2, Kringle containing protein marking the eye and the nose, Kringle containing transmembrane protein 2, Kringle domain containing transmembrane protein 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KRM 2, KRM2, MGC10791, MGC16709.

    Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

    Gene ID
    79412
    UniProt
    Q8NCW0
    Pathways
    WNT Signaling
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