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SPCS2 antibody (AA 2-100)

SPCS2 Reactivity: Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6945027
  • Target See all SPCS2 Antibodies
    SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-100
    Reactivity
    • 17
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 18
    • 1
    Rabbit
    Clonality
    • 18
    • 1
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPCS2 antibody is un-conjugated
    Application
    • 9
    • 7
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPCS2
    Isotype
    IgG
    Top Product
    Discover our top product SPCS2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))
    Alternative Name
    SPCS2 (SPCS2 Products)
    Synonyms
    RGD1311253 antibody, 5730406I15Rik antibody, AA408713 antibody, mKIAA0102 antibody, SPC25 antibody, signal peptidase complex subunit 2 antibody, signal peptidase complex subunit 2 homolog (S. cerevisiae) antibody, Spcs2 antibody, SPCS2 antibody
    Background

    Synonyms: Microsomal signal peptidase 25 kDa subunit, Signal peptidase complex subunit 2, Signal peptidase complex subunit 2 homolog (S. cerevisiae), SPase 25 kDa subunit, SPCS2, SPCS2_HUMAN.

    Background: SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

    Gene ID
    9789
    UniProt
    Q15005
    Pathways
    Peptide Hormone Metabolism
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