Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

BCL3 antibody (C-Term)

BCL3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6971433
$605.00
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 5 to 7 Business Days
  • Target See all BCL3 Antibodies
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 45
    • 41
    • 3
    • 1
    Human
    Host
    • 51
    • 14
    • 6
    Rabbit
    Clonality
    • 53
    • 18
    Polyclonal
    Conjugate
    • 32
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL3 antibody is un-conjugated
    Application
    • 35
    • 16
    • 13
    • 13
    • 10
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Bcl3 (B-cell lymphoma 3 protein) functions as a transcriptional co-activator that activates through its association with NFkB homodimers. Bcl3 contains seven ankyrin repeats, which are most closely related to those found in IkB proteins. Bcl3 also functions as a form of IkBNFkB p50 subunit inhibiting its translocation to the nucleus. The expression of this gene can be induced by NFkB, which forms a part of the autoregulatory loop that controls the nuclear residence of NFkB p50. Bcl3 is overexpressed in a number of cancers, can transform fibroblasts and induce tumors in nude mice, thus implicating Bcl3 as a proto-oncogene. Bcl3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Purification
    Serum
    Immunogen
    This Bcl3 antibody was raised against a peptide within the C-terminal half of human Bcl3.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    Alternative Name
    Bcl3 (BCL3 Products)
    Synonyms
    BCL3, AI528691, Bcl-3, BCL4, D19S37, B-cell CLL/lymphoma 3, B cell leukemia/lymphoma 3, BCL3, Bcl3
    Background
    Bcl3 (B-cell lymphoma 3 protein) functions as a transcriptional co-activator that activates through its association with NFkB homodimers. Bcl3 contains seven ankyrin repeats, which are most closely related to those found in IkB proteins. Bcl3 also functions as a form of IkBNFkB p50 subunit inhibiting its translocation to the nucleus. The expression of this gene can be induced by NFkB, which forms a part of the autoregulatory loop that controls the nuclear residence of NFkB p50. Bcl3 is overexpressed in a number of cancers, can transform fibroblasts and induce tumors in nude mice, thus implicating Bcl3 as a proto-oncogene.
    Molecular Weight
    60 kDa
    NCBI Accession
    NP_005169
    Pathways
    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
You are here:
Support