CTBP2 antibody (Isoform 1, Isoform 2)

Catalog No. ABIN6971552

Product Details anti-CTBP2 Antibody

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Binding Specificity: Isoform 1, Isoform 2

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP2 antibody is un-conjugated

Application: Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)

Characteristics: The CTBP2 (C-terminal binding protein 2) gene encodes a protein that is a corepressor targeting diverse transcription regulators. It functions in brown adipose tissue (BAT) differentiation. Isoform 2 probably acts as a scaffold for specialized synapses. Isoform 2 is also phosphorylated upon DNA damage, probably by ATM or ATR at Thr179, Ser181 and Ser185. Phosphorylation by HIPK2 on Ser428 induces proteasomal degradation. CTBP2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogen: This CTBP2 antibody was raised against a peptide in the C-terminal region of human CTBP2. This antibody recognizes both isoform 1 and 2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Alternative Name: CTBP2 (CTBP2 Products)

Synonyms: ctbp antibody, ctbp-b antibody, xctbp antibody, AA407280 antibody, D7Ertd45e antibody, Gtrgeo6 antibody, Ribeye antibody, fe05b01 antibody, wu:fb96g03 antibody, wu:fe05b01 antibody, wu:fk19e02 antibody, C-terminal binding protein 2 antibody, C-terminal-binding protein 2 antibody, C-terminal binding protein 2a antibody, C-terminal binding protein 2 S homeolog antibody, ctbp2 antibody, LOC100398309 antibody, CTBP2 antibody, Ctbp2 antibody, ctbp2a antibody, ctbp2.S antibody

Molecular Weight: 50 kDa

NCBI Accession: NP_001077383