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TNFRSF6B antibody

TNFRSF6B Reactivity: Human WB Host: Mouse Monoclonal 37A565 unconjugated
Catalog No. ABIN6971573
$374.00
Plus shipping costs $45.00
100 μg
Shipping to: United States
Delivery in 5 to 7 Business Days
  • Target See all TNFRSF6B Antibodies
    TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
    Reactivity
    • 50
    • 6
    • 5
    Human
    Host
    • 42
    • 8
    Mouse
    Clonality
    • 42
    • 7
    Monoclonal
    Conjugate
    • 25
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF6B antibody is un-conjugated
    Application
    • 33
    • 29
    • 27
    • 21
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Characteristics
    DcR3 (TNFRSF6B or tumor necrosis factor receptor superfamily member 6b) is thought to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. DcR3 acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene. DcR3 antibody (mAb) (Clone 37A565) was raised in a Mouse host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Purification
    Affinity Purified
    Immunogen
    This DcR3 antibody was raised against a full-length protein corresponding to human DcR3.
    Clone
    37A565
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
    Alternative Name
    DcR3 (TNFRSF6B Products)
    Synonyms
    DCR3, DJ583P15.1.1, M68, M68E, TR6, dcr3, m68, tr6, TNF receptor superfamily member 6b, tumor necrosis factor receptor superfamily, member 11b, regulator of telomere elongation helicase 1, TNF receptor superfamily member 6b L homeolog, TNFRSF6B, tnfrsf11b, RTEL1, tnfrsf6b, tnfrsf6b.L
    Background
    DcR3 (TNFRSF6B or tumor necrosis factor receptor superfamily member 6b) is thought to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. DcR3 acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
    Molecular Weight
    34 kDa
    NCBI Accession
    NP_003814
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