SLC7A1 antibody (C-Term)

Catalog No. ABIN6971629

Product Details anti-SLC7A1 Antibody

Target: SLC7A1 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A1 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: ERR-a (Estrogen-related receptor alpha, NR3B1) is an orphan nuclear receptor similar to the Estrogen Receptor. It is a sequence-specific DNA binding transcriptional activator that is constitutively active in the absence of ligand binding. No true physiological ligands have been found, but estrogen-like compounds from plants have been shown to activate ERR-a. ERR-a and ER-a have been found to regulate an overlapping set of genes, and ERR-a appears to modulate the activity of ER-a in some tissue types. ERR-a regulates genes involved in mitochondrial biogenesis, gluconeogenesis, oxidative phosphorylation, and fatty acid metabolism. ERR-a knockout mice display impaired fat metabolism and absorption. ERR-a antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This ERR-alpha antibody was raised against a peptide within the C-terminal region of human ERR alpha.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for SLC7A1

Target: SLC7A1 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 1 (SLC7A1))

Alternative Name: ERR-α (SLC7A1 Products)

Synonyms: ATRC1 antibody, CAT-1 antibody, ERR antibody, HCAT1 antibody, REC1L antibody, CAT1 antibody, CATIONIC AMINO ACID TRANSPORTER 1 antibody, F7J7.60 antibody, F7J7_60 antibody, amino acid transporter 1 antibody, 4831426K01Rik antibody, AI447493 antibody, Atrc-1 antibody, Atrc1 antibody, Cat1 antibody, Rec-1 antibody, Rev-1 antibody, mCAT-1 antibody, Cat-1 antibody, si:ch211-69k21.2 antibody, DKFZp459K194 antibody, solute carrier family 7 member 1 antibody, amino acid transporter 1 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 antibody, cationic amino acid transporter Cat1 antibody, SLC7A1 antibody, AAT1 antibody, Slc7a1 antibody, slc7a1 antibody, cat1 antibody

Molecular Weight: 50 kDa

NCBI Accession: NP_004442

Pathways: Dicarboxylic Acid Transport