TRIM56 antibody (AA 651-755) (Alexa Fluor 488)

Catalog No. ABIN6977508

Product Details anti-TRIM56 Antibody (Alexa Fluor 488)

Target: TRIM56 (Tripartite Motif Containing 56 (TRIM56))

Binding Specificity: AA 651-755

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM56 antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF109/TRIM56

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRIM56

Target: TRIM56 (Tripartite Motif Containing 56 (TRIM56))

Alternative Name: RNF109/TRIM56 (TRIM56 Products)

Synonyms: TRIM56 antibody, RNF109 antibody, A130009K11Rik antibody, Gm452 antibody, tripartite motif containing 56 antibody, tripartite motif-containing 56 antibody, TRIM56 antibody, Trim56 antibody

Background:

Synonyms: A130009K11Rik, DKFZp667O116, E3 ubiquitin-protein ligase TRIM56, FLJ35608, Gm452, MGC37358, OTTMUSP00000027392, RING finger protein 109, RNF109, TRI56_HUMAN, Trim56, Tripartite motif containing protein 56, Tripartite motif-containing protein 56.

Background: E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA (By similarity).

Gene ID: 81844

UniProt: Q9BRZ2