MAGMAS antibody (AA 31-125) (Alexa Fluor 555)

Catalog No. ABIN6978713

Product Details anti-MAGMAS Antibody (Alexa Fluor 555)

Target: MAGMAS (PAM16) (Presequence Translocase-Associated Motor 16 Homolog (PAM16))

Binding Specificity: AA 31-125

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGMAS antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAM16

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAGMAS

Target: MAGMAS (PAM16) (Presequence Translocase-Associated Motor 16 Homolog (PAM16))

Alternative Name: PAM16 (PAM16 Products)

Synonyms: MAGMAS antibody, TIM16 antibody, TIMM16 antibody, 2010110I09Rik antibody, AV006767 antibody, CGI-136 antibody, Magmas antibody, Tim16 antibody, Timm16 antibody, magmas antibody, timm16 antibody, zgc:73356 antibody, cgi-136 antibody, pam16 antibody, pam16-a antibody, pam16-b antibody, tim-16 antibody, tim16 antibody, timm16-b antibody, timm16-a antibody, presequence translocase associated motor 16 antibody, presequence translocase-asssociated motor 16 homolog (S. cerevisiae) antibody, presequence translocase associated motor 16 S homeolog antibody, presequence translocase associated motor 16 L homeolog antibody, PAM16 antibody, Pam16 antibody, pam16 antibody, pam16.S antibody, pam16.L antibody

Background:

Synonyms: CGI-136, MAGMAS, Magmas like protein, Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction, Mitochondria-associated granulocyte macrophage CSF-signaling molecule, Mitochondrial import inner membrane translocase subunit TIM16, PAM16, Presequence translocase-associated motor 16 homolog (S. cerevisiae), Presequence translocated-associated motor subunit PAM16, TIM16, TIM16_HUMAN, TIMM16.

Background: This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]

Gene ID: 51025

UniProt: Q9Y3D7