PNMA3 antibody (AA 351-450) (Alexa Fluor 594)

Catalog No. ABIN6979632

Product Details anti-PNMA3 Antibody (Alexa Fluor 594)

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Binding Specificity: AA 351-450

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNMA3 antibody is conjugated to Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PNMA3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PNMA3

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Alternative Name: PNMA3 (PNMA3 Products)

Synonyms: MA3 antibody, MA5 antibody, RGD1563752 antibody, PNMA family member 3 antibody, paraneoplastic antigen MA3 antibody, paraneoplastic Ma antigen 3 antibody, PNMA3 antibody, Pnma3 antibody

Background:

Synonyms: MA3, MA5, MGC132756, MGC132758, Paraneoplastic antigen Ma3, Paraneoplastic cancer testis brain antigen, Paraneoplastic Ma antigen 3, PNMA 3, PNMA3, PNMA3_MOUSE.

Background: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Gene ID: 245468

UniProt: Q8JZW8