SLC30A8 antibody (AA 1-100) (Biotin)

Catalog No. ABIN6982892

Product Details anti-SLC30A8 Antibody (Biotin)

Target: SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))

Binding Specificity: AA 1-100

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC30A8 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNT8

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SLC30A8

Target: SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))

Alternative Name: ZNT8 (SLC30A8 Products)

Synonyms: C820002P14Rik antibody, ZnT-8 antibody, ZnT8 antibody, slc30a3 antibody, znt8 antibody, ZNT8 antibody, E130106K10Rik antibody, Gm212 antibody, wu:fe49g03 antibody, RGD1305098 antibody, solute carrier family 30 member 8 antibody, solute carrier family 30 (zinc transporter), member 8 antibody, solute carrier family 30 (zinc transporter), member 8 L homeolog antibody, solute carrier family 30, member 10 antibody, SLC30A8 antibody, Slc30a8 antibody, slc30a8.L antibody, slc30a8 antibody, Slc30a10 antibody

Background:

Synonyms: SLC30A8, solute carrier family 30 (zinc transporter), member 8, Solute carrier family 30 member 8, Zinc transporter 8, zinc transporter ZnT-8, ZnT-8, ZNT 8, ZNT8_HUMAN.

Background: ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].

Gene ID: 169026

UniProt: Q8IWU4

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis