SARS-CoV-2 NSP8 antibody (AA 60-110)

Catalog No. ABIN6990137

Product Details anti-SARS-CoV-2 NSP8 Antibody

Target: SARS-CoV-2 NSP8 (NSP8) (SARS-CoV-2 Non-Structural Protein 8 (NSP8))

Binding Specificity: AA 60-110

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS-CoV-2 NSP8 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: SARS-CoV-2 (COVID-19) NSP8 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) NSP8 antibody was raised against a peptide corresponding to 14 amino acids near the center of SARS-CoV-2 (COVID-19) NSP8 protein. The immunogen is located within 60-110 amino acids of SARS-CoV-2 (COVID-19) NSP8.

Isotype: IgG

Application Details

Application Notes: IHC: 0.5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP8 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 NSP8 recombinant protein by ELISA. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) NSP8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SARS-CoV-2 (COVID-19) NSP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SARS-CoV-2 NSP8

Target: SARS-CoV-2 NSP8 (NSP8) (SARS-CoV-2 Non-Structural Protein 8 (NSP8))

Alternative Name: SARS-CoV-2 NSP8 (NSP8 Products)

Synonyms: pp1ab antibody, ORF1a polyprotein;ORF1ab polyprotein antibody, ORF1ab antibody

Target Type: Viral Protein

Background: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP8 plays a role in viral RNA synthesis (3,4,5). Forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, it may synthesize substantially longer products than oligonucleotide primers (6).

Gene ID: 43740578

NCBI Accession: YP_009742615

UniProt: P0DTC1