Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Purification
CTRP5 Antibody is affinity chromatography purified via peptide column.
Immunogen
CTRP5 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human CTRP5. The immunogen is located within amino acids 30 - 80 of CTRP5.
CTRP5 antibody can be used for the detection of CTRP5 by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
CTRP5 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
CTRP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CTRP5 (C1QTNF5)
(C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
C1QTNF5 antibody, wu:fb02c10 antibody, wu:fb02f05 antibody, zgc:112378 antibody, CTRP5 antibody, Ctrp5 antibody, C1q and tumor necrosis factor related protein 5 antibody, C1q and TNF related 5 antibody, C1QTNF5 antibody, c1qtnf5 antibody, C1qtnf5 antibody
Background
CTRP5 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.