SLITRK4 antibody (N-Term)

Catalog No. ABIN6990856

Product Details anti-SLITRK4 Antibody

Target: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Binding Specificity: AA 30-80, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Purification: Slitrk4 Antibody is affinity chromatography purified via peptide column.

Immunogen: Slitrk4 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Slitrk4. The immunogen is located within amino acids 30 - 80 of Slitrk4.

Isotype: IgG

Application Details

Application Notes: Slitrk4 antibody can be used for detection of Slitrk4 by Western blot at 0.5 and 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Slitrk4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Slitrk4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLITRK4

Target: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Alternative Name: Slitrk4 (SLITRK4 Products)

Synonyms: 6430513G13 antibody, D930039I09Rik antibody, SLIT and NTRK like family member 4 antibody, SLIT and NTRK-like family, member 4 antibody, cyclic nucleotide gated channel alpha 2 antibody, SLITRK4 antibody, slitrk4 antibody, Slitrk4 antibody, CNGA2 antibody

Background: Slitrk4 Antibody: SLIT and NTRK-like family 4 (Slitrk4) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk4 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

Gene ID: 139065

UniProt: Q8IW52