Klra3 antibody (C-Term)

Catalog No. ABIN6991049

Product Details anti-Klra3 Antibody

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Klra3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody may cross-react with other LY49 receptors.

Purification: KLRA3 Antibody is affinity chromatography purified via peptide column.

Immunogen: KLRA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA3. The immunogen is located within the last 50 amino acids of KLRA3.

Isotype: IgG

Application Details

Application Notes: KLRA3 antibody can be used for detection of KLRA3 by Western blot at 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: KLRA3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: KLRA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Klra3

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Alternative Name: KLRA3 (Klra3 Products)

Background: KLRA3 Antibody: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.

Gene ID: 16634

UniProt: Q64329