LRFN5 antibody (C-Term)

Catalog No. ABIN6991082

Product Details anti-LRFN5 Antibody

Target: LRFN5 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 5 (LRFN5))

Binding Specificity: AA 650-700, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRFN5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: At least two isoforms of LRFN5 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.

Purification: LRFN5 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRFN5 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human LRFN5. The immunogen is located within amino acids 650 - 700 of LRFN5.

Isotype: IgG

Application Details

Application Notes: LRFN5 antibody can be used for detection of LRFN5 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRFN5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LRFN5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LRFN5

Target: LRFN5 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 5 (LRFN5))

Alternative Name: LRFN5 (LRFN5 Products)

Synonyms: C14orf146 antibody, FIGLER8 antibody, SALM5 antibody, AI427653 antibody, AI604817 antibody, C130061B21 antibody, mKIAA4208 antibody, leucine rich repeat and fibronectin type III domain containing 5 antibody, LRFN5 antibody, Lrfn5 antibody

Background: LRFN5 Antibody: LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Gene ID: 145581

UniProt: Q96NI6