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FAM59A antibody (C-Term)

FAM59A Reactivity: Human, Mouse, Rat ELISA, WB, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991222
  • Target See all FAM59A Antibodies
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    Binding Specificity
    • 15
    • 5
    • 1
    AA 630-680, C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM59A antibody is un-conjugated
    Application
    • 16
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    FAM59A Antibody is affinity chromatography purified via peptide column.
    Immunogen
    FAM59A antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAM59A. The immunogen is located within amino acids 630 - 680 of FAM59A.
    Isotype
    IgG
    Top Product
    Discover our top product FAM59A Primary Antibody
  • Application Notes
    FAM59A antibody can be used for detection of FAM59A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    FAM59A Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    FAM59A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    Alternative Name
    FAM59A (FAM59A Products)
    Synonyms
    C18orf11 antibody, FAM59A antibody, Gm944 antibody, C86169 antibody, Fam59a antibody, mKIAA4238 antibody, fam59a antibody, zgc:55634 antibody, GRB2 associated regulator of MAPK1 subtype 1 antibody, GRB2 associated, regulator of MAPK1 antibody, GAREM1 antibody, Garem1 antibody, garem antibody
    Background
    FAM59A Antibody: FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
    Gene ID
    64762
    UniProt
    Q9H706
    Pathways
    EGFR Signaling Pathway
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