ZC3H12B antibody (N-Term)

Catalog No. ABIN6991307

Product Details anti-ZC3H12B Antibody

Target: ZC3H12B (Zinc Finger CCCH-Type Containing 12B (ZC3H12B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H12B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: ZC3H12B Antibody is affinity chromatography purified via peptide column.

Immunogen: ZC3H12B antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12B. The immunogen is located within the first 50 amino acids of ZC3H12B.

Isotype: IgG

Application Details

Application Notes: ZC3H12B antibody can be used for detection of ZC3H12B by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZC3H12B Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZC3H12B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZC3H12B

Target: ZC3H12B (Zinc Finger CCCH-Type Containing 12B (ZC3H12B))

Alternative Name: ZC3H12B (ZC3H12B Products)

Synonyms: CXorf32 antibody, MCPIP2 antibody, A130028J20Rik antibody, Gm373 antibody, RGD1560891 antibody, zinc finger CCCH-type containing 12B antibody, ZC3H12B antibody, Zc3h12b antibody, zc3h12b antibody

Background: ZC3H12B Antibody: ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).

Gene ID: 340554

NCBI Accession: NP_001010888

UniProt: Q5HYM0