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NALP8 antibody (N-Term)

NLRP8 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991405
  • Target See all NALP8 (NLRP8) Antibodies
    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
    Binding Specificity
    AA 130-180, N-Term
    Reactivity
    Human
    Host
    • 2
    • 1
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This NALP8 antibody is un-conjugated
    Application
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    NALP8 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8. The immunogen is located within amino acids 130 - 180 of NALP8.
    Isotype
    IgG
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  • Application Notes
    NALP8 antibody can be used for detection of NALP8 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    NALP8 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    NALP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
    Alternative Name
    NALP8 (NLRP8 Products)
    Synonyms
    CLR19.2 antibody, NALP8 antibody, NOD16 antibody, PAN4 antibody, NLR family pyrin domain containing 8 antibody, NLRP8 antibody
    Background
    NALP8 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
    Gene ID
    126205
    NCBI Accession
    NP_789781
    UniProt
    Q86W28
    Pathways
    Inflammasome
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