NLRP14 antibody (N-Term)

Catalog No. ABIN6991410

Product Details anti-NLRP14 Antibody

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Binding Specificity: AA 200-250, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: NALP14 Antibody is affinity chromatography purified via peptide column.

Immunogen: NALP14 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP14. The immunogen is located within amino acids 200 - 250 of NALP14.

Isotype: IgG

Application Details

Application Notes: NALP14 antibody can be used for detection of NALP14 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NALP14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NALP14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NLRP14

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Alternative Name: NALP14 (NLRP14 Products)

Synonyms: 4921520L01Rik antibody, GC-LRR antibody, Nalp-iota antibody, Nalp14 antibody, Nalp14l antibody, NALP14 antibody, CLR11.2 antibody, NOD5 antibody, PAN8 antibody, NLR family, pyrin domain containing 14 antibody, NLR family pyrin domain containing 14 antibody, Nlrp14 antibody, NLRP14 antibody

Background: NALP14 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.

Gene ID: 338323

NCBI Accession: NP_789792

UniProt: Q86W24

Pathways: Inflammasome