ZMIZ2 antibody (AA 270-320)

Catalog No. ABIN6991507

Product Details anti-ZMIZ2 Antibody

Target: ZMIZ2 (Zinc Finger, MIZ-Type Containing 2 (ZMIZ2))

Binding Specificity: AA 270-320

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMIZ2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.

Purification: ZIMP7 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7. The immunogen is located within amino acids 270 - 320 of ZIMP7.

Isotype: IgG

Application Details

Application Notes: ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIMP7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZIMP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZMIZ2

Target: ZMIZ2 (Zinc Finger, MIZ-Type Containing 2 (ZMIZ2))

Alternative Name: ZIMP7 (ZMIZ2 Products)

Synonyms: MGC86475 antibody, RGD1309256 antibody, zimp7 antibody, hzimp7 antibody, NET27 antibody, TRAFIP20 antibody, ZIMP7 antibody, hZIMP7 antibody, 2410117E06Rik antibody, D11Bwg0280e antibody, R74931 antibody, Zimp7 antibody, zinc finger, MIZ-type containing 2 S homeolog antibody, zinc finger, MIZ-type containing 2 antibody, zinc finger MIZ-type containing 2 antibody, zmiz2.S antibody, ZMIZ2 antibody, zmiz2 antibody, Zmiz2 antibody

Background: ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.

Gene ID: 83637

UniProt: Q8NF64