ZMIZ1 antibody (N-Term)

Catalog No. ABIN6991508

Product Details anti-ZMIZ1 Antibody

Target: ZMIZ1 (Zinc Finger, MIZ-Type Containing 1 (ZMIZ1))

Binding Specificity: AA 90-140, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMIZ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: At least three isoforms are known to exist, this antibody will recognize all three. ZIMP10 antibody is predicted to not cross-react with other PIAS protein family members.

Purification: ZIMP10 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZIMP10 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIMP10. The immunogen is located within amino acids 90 - 140 of ZIMP10.

Isotype: IgG

Application Details

Application Notes: ZIMP10 antibody can be used for detection of ZIMP10 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIMP10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZIMP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZMIZ1

Target: ZMIZ1 (Zinc Finger, MIZ-Type Containing 1 (ZMIZ1))

Alternative Name: ZIMP10 (ZMIZ1 Products)

Synonyms: miz antibody, rai17 antibody, zimz1 antibody, zimp10 antibody, hzimp10 antibody, MIZ antibody, RAI17 antibody, TRAFIP10 antibody, ZIMP10 antibody, hZIMP10 antibody, BC065120 antibody, E330020C23 antibody, ENSMUSG00000072684 antibody, Gm10397 antibody, I920194n01 antibody, Rai17 antibody, Zimp10 antibody, wu:fb80e10 antibody, zgc:175159 antibody, zmiz1 antibody, zinc finger MIZ-type containing 1 antibody, zinc finger, MIZ-type containing 1 antibody, zinc finger, MIZ-type containing 1a antibody, ZMIZ1 antibody, zmiz1 antibody, Zmiz1 antibody, zmiz1a antibody

Background: ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5, these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.

Gene ID: 57178

NCBI Accession: NP_65071

UniProt: Q9ULJ6