ATAD3B antibody (C-Term)

Catalog No. ABIN6991548

Product Details anti-ATAD3B Antibody

Target: ATAD3B (ATPase Family, AAA Domain Containing 3B (ATAD3B))

Binding Specificity: AA 570-620, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATAD3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: ATAD3B antibody is predicted to not cross-react with other ATAD protein family members. At least three isoforms of ATAD3B are known to exist.

Purification: ATAD3B Antibody is affinity chromatography purified via peptide column.

Immunogen: ATAD3B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human ATAD3B. The immunogen is located within amino acids 570 - 620 of ATAD3B.

Isotype: IgG

Application Details

Application Notes: ATAD3B antibody can be used for detection of ATAD3B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ATAD3B Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ATAD3B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ATAD3B

Target: ATAD3B (ATPase Family, AAA Domain Containing 3B (ATAD3B))

Alternative Name: ATAD3B (ATAD3B Products)

Synonyms: AAA-TOB3 antibody, TOB3 antibody, atad3b antibody, zgc:77371 antibody, ATPase family, AAA domain containing 3B antibody, ATPase family, AAA domain containing 3 antibody, ATAD3B antibody, atad3 antibody

Background: ATAD3B Antibody: ATAD3B is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.

Gene ID: 83858

NCBI Accession: NP_114127

UniProt: Q5T9A4