KPNA5 antibody (N-Term)

Catalog No. ABIN6991635

Product Details anti-KPNA5 Antibody

Target: KPNA5 (Karyopherin alpha 5 (Importin alpha 6) (KPNA5))

Binding Specificity: AA 50-100, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KPNA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: KPNA5 antibody is predicted to not cross-react with other Importin alpha family members.

Purification: KPNA5 Antibody is affinity chromatography purified via peptide column.

Immunogen: KPNA5 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human KPNA5. The immunogen is located within amino acids 50 - 100 of KPNA5.

Isotype: IgG

Application Details

Application Notes: KPNA5 antibody can be used for detection of EPAC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: KPNA5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: KPNA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KPNA5

Target: KPNA5 (Karyopherin alpha 5 (Importin alpha 6) (KPNA5))

Alternative Name: KPNA5 (KPNA5 Products)

Synonyms: IPOA6 antibody, SRP6 antibody, Ipoa6 antibody, im:7151662 antibody, zgc:110662 antibody, karyopherin subunit alpha 5 antibody, karyopherin alpha 5 (importin alpha 6) antibody, KPNA5 antibody, Kpna5 antibody, kpna5 antibody

Background: KPNA5 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA5 belongs to a subfamily within the KPNA family that also includes KPNA4 and 6 and is thought to be involved in NLS-dependent protein imort into the nucleus.

Gene ID: 3841

UniProt: O15131

Pathways: Protein targeting to Nucleus