KNSTRN antibody

Catalog No. ABIN7233849

Product Details anti-KNSTRN Antibody

Target: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KNSTRN antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant Human Small kinetochore-associated protein protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KNSTRN

Target: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Alternative Name: C15orf23 (KNSTRN Products)

Synonyms: 1700025D04Rik antibody, C15orf23 antibody, D2Ertd750e antibody, SKAP antibody, Traf4af1 antibody, TRAF4AF1 antibody, kinetochore-localized astrin/SPAG5 binding antibody, kinetochore localized astrin/SPAG5 binding protein antibody, kinetochore-localized astrin/SPAG5 binding protein antibody, Knstrn antibody, KNSTRN antibody

Background: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.

Molecular Weight:

Observed_MW: 35 kDa

Calculated_MW: 35 kDa

UniProt: Q9Y448

Pathways: M Phase