Nebulin antibody

Catalog No. ABIN7238231

Product Details anti-Nebulin Antibody

Target: Nebulin (NEB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nebulin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human NEB

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Nebulin

Target: Nebulin (NEB)

Alternative Name: NEB (NEB Products)

Synonyms: im:6904860 antibody, im:7001777 antibody, im:7144538 antibody, im:7150492 antibody, wu:fc33b04 antibody, si:ch211-168m7.5 antibody, NEB antibody, NEB177D antibody, NEM2 antibody, AI595938 antibody, nebulin antibody, neb antibody, NEB antibody, Neb antibody, LOC100516703 antibody

Target Type: Chemical

Background: This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4 % of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.

NCBI Accession: NP_001157979

UniProt: P20929