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NLRP10 antibody

NLRP10 Reactivity: Human, Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7001412
  • Target See all NLRP10 Antibodies
    NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
    Reactivity
    • 47
    • 8
    • 1
    Human, Mouse
    Host
    • 46
    • 1
    • 1
    Rabbit
    Clonality
    • 47
    • 1
    Polyclonal
    Conjugate
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP10 antibody is un-conjugated
    Application
    • 22
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human NLRP10
    Isotype
    IgG
    Top Product
    Discover our top product NLRP10 Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.1 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
    Alternative Name
    NLRP10 (NLRP10 Products)
    Synonyms
    CLR11.1 antibody, NALP10 antibody, NOD8 antibody, PAN5 antibody, PYNOD antibody, 6430548I20Rik antibody, Nalp10 antibody, Napl10 antibody, Pynod antibody, NLR family pyrin domain containing 10 antibody, NLR family, pyrin domain containing 10 antibody, NLRP10 antibody, Nlrp10 antibody
    Background
    Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
    Molecular Weight
    75 kDa
    NCBI Accession
    NP_789791
    UniProt
    Q86W26
    Pathways
    Inflammasome
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