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C14orf169 + NO66 antibody

C14orf169 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7244582
  • Target See all C14orf169 + NO66 (C14orf169) Antibodies
    C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
    Reactivity
    • 15
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 12
    • 2
    • 1
    Rabbit
    Clonality
    • 14
    • 1
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C14orf169 + NO66 antibody is un-conjugated
    Application
    • 8
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human C14orf169
    Isotype
    IgG
    Top Product
    Discover our top product C14orf169 Primary Antibody
  • Application Notes
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.8 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
    Alternative Name
    C14orf169 (C14orf169 Products)
    Synonyms
    LOC453015 antibody, C10H14orf169 antibody, MAPJD antibody, NO66 antibody, ROX antibody, C14orf169 antibody, No66 antibody, im:7141580 antibody, no66 antibody, chromosome 14 open reading frame 169 antibody, ribosomal oxygenase 1 antibody, chromosome 5 open reading frame, human C14orf169 antibody, LOC453015 antibody, Bm1_08415 antibody, RIOX1 antibody, C5H14ORF169 antibody, Riox1 antibody, riox1 antibody
    Background
    Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation.
    UniProt
    Q9H6W3
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