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UNC45B antibody

UNC45B Reactivity: Human, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7252228
  • Target See all UNC45B Antibodies
    UNC45B (Unc-45 Homolog B (UNC45B))
    Reactivity
    • 32
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 30
    • 2
    • 1
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC45B antibody is un-conjugated
    Application
    • 21
    • 19
    • 14
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Fusion protein of human UNC45B
    Isotype
    IgG
    Top Product
    Discover our top product UNC45B Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    UNC45B (Unc-45 Homolog B (UNC45B))
    Alternative Name
    UNC45B (UNC45B Products)
    Synonyms
    MGC80931 antibody, cmya4 antibody, AA445617 antibody, Cmya4 antibody, D230041A13Rik antibody, Unc45 antibody, CMYA4 antibody, SMUNC45 antibody, UNC45 antibody, Unc-45B antibody, cb393 antibody, unc45r antibody, wu:fa05a03 antibody, wu:fa10f03 antibody, wu:fb37f02 antibody, wu:fb96f06 antibody, wu:fc10f04 antibody, unc-45 myosin chaperone B S homeolog antibody, unc-45 myosin chaperone B antibody, unc45b.S antibody, unc45b antibody, UNC45B antibody, Unc45b antibody
    Background
    This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 104/95 kDa

    UniProt
    Q8IWX7
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