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TGFBR2 antibody
TGFBR2
Reactivity: Human, Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TGFBR2 Antibody
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Target
See all TGFBR2 Antibodies
TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Reactivity
All reactivities for TGFBR2 antibodies
Human, Mouse, Rat
Host
All hosts for TGFBR2 antibodies
Rabbit
Clonality
All clonalities for TGFBR2 antibodies
Polyclonal
Conjugate
All conjugates for TGFBR2 antibodies
This TGFBR2 antibody is un-conjugated
Application
All applications for TGFBR2 antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human TGFBR2 (NP_003233.4).
Isotype
IgG
Top Product
Discover our top product TGFBR2 Primary Antibody
Alternatives
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anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 241-330) antibody
TGFBR2
Reactivity: Human, Mouse, Rat, Rabbit, Cow
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TGFBR2
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Target
TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Alternative Name
TGFBR2 (TGFBR2 Products )
Synonyms
AAT3 antibody, FAA3 antibody, LDS1B antibody, LDS2B antibody, MFS2 antibody, RIIC antibody, TAAD2 antibody, TGFR-2 antibody, TGFbeta-RII antibody, 1110020H15Rik antibody, AU042018 antibody, DNIIR antibody, RIIDN antibody, TBR-II antibody, TbetaR-II antibody, TbetaRII antibody, TGFBR2 antibody, TBETA-RII antibody, TGFBRII antibody, TGF-beta 2 antibody, Tgfbr2T antibody, cb537 antibody, tgfbr2 antibody, wu:fj05c10 antibody, zgc:110498 antibody, transforming growth factor beta receptor 2 antibody, transforming growth factor, beta receptor II antibody, transforming growth factor, beta receptor 2 antibody, transforming growth factor beta receptor 2b antibody, TGFBR2 antibody, Tgfbr2 antibody, tgfbr2b antibody
Background
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Gene ID
7048
UniProt
P37173
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