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ETV1 antibody

ETV1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7256808
  • Target See all ETV1 Antibodies
    ETV1 (Ets Variant 1 (ETV1))
    Reactivity
    • 32
    • 32
    • 21
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 43
    • 3
    • 1
    Rabbit
    Clonality
    • 45
    • 2
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ETV1 antibody is un-conjugated
    Application
    • 34
    • 17
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ETV1 (NP_004947.2).
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ETV1 (Ets Variant 1 (ETV1))
    Alternative Name
    ETV1 (ETV1 Products)
    Synonyms
    er81 antibody, XER81 antibody, MGC75591 antibody, ER81 antibody, Etsrp81 antibody, ETS variant 1 antibody, ets variant 1 antibody, ETS variant 1 S homeolog antibody, etv1 antibody, ETV1 antibody, Etv1 antibody, etv1.S antibody
    Background
    This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
    Gene ID
    2115
    UniProt
    P50549
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