OPRK1 antibody

Catalog No. ABIN7257593

Product Details anti-OPRK1 Antibody

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human OPRK1 (NP_000903.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Alternative Name: OPRK1 (OPRK1 Products)

Synonyms: OPRK1 antibody, LOC780448 antibody, kor antibody, KOR antibody, OPRK antibody, K-OR-1 antibody, KOR-1 antibody, MSL-1 antibody, Oprk2 antibody, R21 antibody, opioid receptor, kappa 1 antibody, opioid receptor kappa 1 antibody, oprk1 antibody, OPRK1 antibody, Oprk1 antibody

Background: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molecular Weight:

Observed_MW: 40 kDa

Calculated_MW: 33 kDa/42 kDa

Gene ID: 4986

UniProt: P41145