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IQGAP3 antibody

IQGAP3 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7257710
  • Target See all IQGAP3 products
    IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))
    Reactivity
    • 25
    • 12
    • 4
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 5
    Rabbit
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IQGAP3 antibody is un-conjugated
    Application
    • 17
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human IQGAP3 (NP_839943.2).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))
    Alternative Name
    IQGAP3 (IQGAP3 Products)
    Synonyms
    IQGAP3 antibody, AI593484 antibody, D030034H08 antibody, IQ motif containing GTPase activating protein 3 antibody, IQGAP3 antibody, iqgap3 antibody, Iqgap3 antibody
    Background
    IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
    Molecular Weight

    Observed_MW: 170 kDa

    Calculated_MW: 184 kDa

    Gene ID
    128239
    UniProt
    Q86VI3
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