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- Target See all NUAK1 Antibodies
- NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUAK1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human NUAK1 (NP_055655.1).
- Isotype
- IgG
- Top Product
- Discover our top product NUAK1 Primary Antibody
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anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 1-30), (N-Term) antibody
NUAK1 Reactivity: Human, Mouse, Hamster WB, IHC (p) Host: Rabbit Polyclonal RB3520 unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 604-634), (C-Term) antibodyNUAK1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB3521 unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 451-550) antibodyNUAK1 Reactivity: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 1-661) antibodyNUAK1 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 404-651) antibodyNUAK1 Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (C-Term) antibodyNUAK1 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) antibodyNUAK1 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (Internal Region) antibodyVerified NUAK1 Reactivity: Human ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 362-661) antibodyNUAK1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-NUAK Family, SNF1-Like Kinase, 1 (NUAK1) (AA 421-658) antibodyNUAK1 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:200-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NUAK1 (NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
- Alternative Name
- NUAK1 (NUAK1 Products)
- Synonyms
- ARK5 antibody, AU014801 antibody, AW494241 antibody, B230104P22Rik antibody, Omphk1 antibody, NUAK family kinase 1 antibody, NUAK family, SNF1-like kinase, 1 antibody, NUAK1 antibody, Nuak1 antibody
- Background
- NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.
- Molecular Weight
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Observed_MW: 74 kDa
Calculated_MW: 23 kDa/74 kDa
- Gene ID
- 9891
- UniProt
- O60285
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