CLCN7 antibody

Catalog No. ABIN7262785

Product Details anti-CLCN7 Antibody

Target: CLCN7 (Chloride Channel, Voltage-Sensitive 7 (CLCN7))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN7 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CLCN7 (NP_001278.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLCN7

Target: CLCN7 (Chloride Channel, Voltage-Sensitive 7 (CLCN7))

Alternative Name: CLCN7 (CLCN7 Products)

Synonyms: CLC-7 antibody, CLC7 antibody, OPTA2 antibody, OPTB4 antibody, PPP1R63 antibody, AA409691 antibody, AW538136 antibody, ClC-7 antibody, D17Wsu51e antibody, MGC80627 antibody, im:7155923 antibody, zgc:153490 antibody, CLCN7 antibody, chloride voltage-gated channel 7 antibody, chloride channel, voltage-sensitive 7 antibody, chloride channel, voltage-sensitive 7 L homeolog antibody, chloride channel 7 antibody, chloride channel protein 7 antibody, CLCN7 antibody, Clcn7 antibody, clcn7.L antibody, clcn7 antibody, CpipJ_CPIJ008618 antibody

Background: The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Gene ID: 1186

UniProt: P51798