TLK1 antibody (AA 458-560)

Catalog No. ABIN701155

Product Details anti-TLK1 Antibody

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Binding Specificity: AA 458-560

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TLK1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Alternative Name: TLK1 (TLK1 Products)

Synonyms: PKU-beta antibody, 4930545J15Rik antibody, fe11e12 antibody, si:dkey-251e16.4 antibody, tlk1 antibody, wu:fe11e12 antibody, TLK1 antibody, fb76h12 antibody, si:dkey-88m1.1 antibody, wu:fb76h12 antibody, DKFZp459L163 antibody, tousled like kinase 1 antibody, tousled-like kinase 1 antibody, tousled-like kinase 1b antibody, tousled like kinase 1 like antibody, serine/threonine-protein kinase TOUSLED antibody, tousled-like kinase 1a antibody, Serine/threonine-protein kinase tousled-like 1 antibody, TLK1 antibody, Tlk1 antibody, tlk1b antibody, TLK1L antibody, LOC542181 antibody, tlk1a antibody, tlk1 antibody, tlk-1 antibody

Background:

Synonyms: PKU beta, serine threonine protein kinase, Serine/threonine protein kinase tousled like 1, TLK1, Tousled like kinase 1.

Background: TLK1 is a nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. TLK1 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin.

Gene ID: 9874