TMEM43 antibody

Catalog No. ABIN7264559

Product Details anti-TMEM43 Antibody

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM43 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TMEM43 (NP_077310.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Alternative Name: TMEM43 (TMEM43 Products)

Synonyms: zgc:85946 antibody, ARVC5 antibody, ARVD5 antibody, EDMD7 antibody, LUMA antibody, 1200015A22Rik antibody, transmembrane protein 43 antibody, TMEM43 antibody, tmem43 antibody, Tmem43 antibody

Background: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Molecular Weight:

Observed_MW: 45 kDa

Calculated_MW: 44 kDa

Gene ID: 79188

UniProt: Q9BTV4